Scott Z. Burns' screenplay follows an outbreak of a deadly virus across four continents and is told from the perspective of various characters with intersecting plot threads
Ho will play the sister of Patient Zero, the first diagnosed case--a casino worker who spreads a deadly virus to passengers on an airplane leaving for the United States.
Matt Damon, Kate Winslet, Marion Cotillard, Laurence Fishburne, Gwyneth Paltrow, Jude Law and John Hawkes also star.
Shooting kicks off in Hong Kong later this month for a release next October.
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