Natalie Portman will star in and produce the indie stoner road comedy "Best Buds" says Pajiba.
Jamie Denbo's script follows two best female friends who set out on a road trip, with a bunch of weed in tow, to a friend's wedding.
A director search is currently underway.
Portman will take this one on after completing work on Pride and Prejudice and Zombies
Portman is currently filming the comic book pic Thor
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