Speaking to Black Book Magazine Neve Campbell says that she's "pretty sure at this stage that Wes [Craven] is back on board to direct" Scream 4.
As for the also returning David Arquette and Courteney Cox--She says:
"I haven't spoken to them in a while. I'm sure it took a while to convince them to take part [in the picture], especially because they're now a very happy family, and of course, it was a long journey for them. I think it's going to be a lot of fun, and a lot like going back to summer camp."
She has yet to read Kevin Williamson.'s script yet - "No. Not yet. They had to wait for us all to sign on. I suppose that’s the way these days."
Filming is due to begin on the sequel in mid-April.